Figure 2.

Effect of PWE on blood lipid profile, enzymatic activity, and clinical biochemistry in mice. (a) PWE slightly decreased the nonesterified fatty acids in mice fed with a high‐fat diet, but this difference failed to reach a significant level. (b) There was no significant difference in the levels of several enzymes (ALT, AST, ALP, and LDH) between the DIO mice and the VC mice. PWE decreased the AST at both low and high doses, whereas only a high dose of PWE decreased LDH in DIO mice. (c) A high dose of PWE significantly lowered the CREA content in mice. Value = means ± SD (n = 6), *p < 0.05, **p < 0.01, LP/HP compared with NC. ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; CREA: creatinine; HP, high dose; LDH: lactic dehydrogenase; LP: low dose; NC: negative control; VC: vehicle control