Figure 3.

Effects of PWE on serum concentration of glucose and GTT in mice. (a) The DIO mice had a significantly higher glucose level compared with VC. Low dose or high dose of PWE reduced the blood glucose level to nearly normal. (b) The glucose concentration of DIO mice was significantly higher than that of the normal mice. PWE at either low or high doses significantly reduced glucose levels to nearly normal after 8 weeks. (c) High‐fat diet‐induced glucose intolerance in mice, while PWE reversed this condition. Area under curve was referred to the area under the curve of the glucose level from 0 to 120 min postinjection. There was a significant difference in glucose level and GTT between the VC mice and the NC mice, whereas no significant difference was found between LP mice and HP mice. Value = means ± SD (n = 6), * p < 0.05, ** p < 0.01 between LP and NC groups, # p < 0.05, ## p < 0.01 between HP and NC groups. HP: high dose; LP: low dose; NC: negative control; VC: vehicle control