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. 2019 Apr 19;18:1534735419843999. doi: 10.1177/1534735419843999

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Cardiac function in the isolated perfused working heart. CR + DOX and CR + WR + DOX had significantly increased LVDP (A) and ESP (B) compared with DOX. The maximal rate of left ventricle pressure development (C) was significantly greater in CR + DOX and CR + WR + DOX compared with DOX, while the minimum rate of left ventricle pressure development (D) was significantly decreased in CR + WR + DOX compared with DOX. Dashed line represents CON group data. Data are mean ± SEM. *P < .05 versus CON. ^#P < .05 versus DOX.