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Animal Characteristicsa.
| n | Body Mass (g) | Heart–Body Ratio (kg:g) | |
|---|---|---|---|
| CON | 6 | 292 (41) | 4.1 (0.9) |
| CR | 6 | 234 (10)* | 5.2 (0.4) |
| WR | 6 | 264 (38) | 4.9 (1.1) |
| CR + WR | 7 | 207 (12)*+ | 4.8 (0.5) |
| DOX | 8 | 242 (34)* | 4.3 (1.0) |
| WR + DOX | 6 | 220 (30)*+ | 4.9 (1.1) |
| CR + DOX | 6 | 221 (11)*+ | 4.1 (0.4) |
| CR + WR + DOX | 8 | 199 (10)*#+ | 4.6 (0.5) |
Abbreviation: CON, control; CR, calorie restriction; WR, wheel running; DOX, doxorubicin.
Data are mean (SD).
P < .05 versus CON. #P < .05 versus DOX. +P < .05 versus WR.
