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. 2019 Apr 19;11:1759091419843393. doi: 10.1177/1759091419843393

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© The Author(s) 2019

Creative Commons CC BY: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 8. — Altered expression patterns of Cd68 in Tpp1^–^/^– 4-month-old brains. Expression pattern of CD68 mRNA in cerebellum (a and b) and forebrain (c to f) in Tpp1^–^/^– (b, d, e, f) and control (a, c) 4-month-old brains by in situ hybridization (blue staining). (e) and (f) represent an enlargement of sections boxed in (d). Quantification of the number of CD68⁺ cell per mm² and cell size (in pixels) for Tpp1^–^/^– cortex and thalamus are compared in (g). Black arrowhead indicates CD68⁺ cells in granular cell layer of Tpp1^–^/^– cerebellum. Scale bars: (a) and (b) = 200 μm; (c) and (d) = 500 μm; (e) and (f) = 50 μm.

ML = molecular layer; GL = granular layer; WM = white matter; CTX = cortex; cc = corpus callosum; HP = hippocampus; TH = thalamus; mfb = medial forebrain bundle.