Table 4.
The effect of GK-2 on the morphometric parameters of rat pancreatic islets
Group | Total β-cell area | Mean islet area, μm2 | Number of islets | ||
---|---|---|---|---|---|
absolute, μm2 | % of the islet area | ||||
1 | Passive control | 259,925±46,353 | 19.9±2.3 | 20,088±3,920 | 13±2 |
2 | Active control | 79,131±21,266** | 8.3±2.1** | 5,983±1,805** | 14±3 |
3 | Intraperitoneal GK-2 | 180,076±36,026* | 13.3±1.7* | 15,567±3,820* | 12±3 |
4 | Oral GK-2 | 175,907±31,357 | 14.0±2.0* | 15,167±1,895* | 12±2 |
*– Statistical significance of differences between the experimental group and active control, p < 0.05.
**– Statistical significance of differences between passive and active control, p < 0.05.