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. Author manuscript; available in PMC: 2019 Apr 22.
Published in final edited form as: J Control Release. 2017 Nov 13;269:364–373. doi: 10.1016/j.jconrel.2017.11.021

Fig. 1.

Fig. 1.

Functional T cells are required for the full efficacy of CP-Dox. Immunocompetent BALB/c mice (dashed lines) or Nude (BALB/c (nu/nu), solid lines) mice lacking functional T cells were inoculated with 4T1 mammary carcinoma in the mammary fat pad. (A) Primary tumor volume and (B) Survival (n = 7 CP-Dox, 7 Free Dox, 6 PBS for Nude and BALB/c groups in D,E). Tumor growth curves analyzed by two-way ANOVA and Tukey’s post hoc, survival by log-rank. *p < 0.05.