Table 1.
Local-regional and local relapse values obtained in the different treatment schedules of the START trials3. Each schedule is characterized by the total dose imparted to patients, D, the dose per fraction, d, and the overall treatment time of the fractionated schedule, T. The relapses, R, found after 5 and 10 years follow ups are given in terms of the average and the 95% confidence interval (between brackets)
| R (%) | ||||||||
| Local-regional relapse | Local relapse | |||||||
| Trial | D (Gy) | d (Gy) | T (week) | 5 year | 10 year | 5 year | 10 year | |
| START A | A1 | 50.0 | 2.00 | 5 | 4.0 [2.8,5.7] | 7.4 [5.5,10.0] | 3.4 [2.3,5.1] | 6.7 [4.9,9.2] |
| A2 | 41.6 | 3.20 | 5 | 3.8 [2.6,5.5] | 6.3 [4.7,8.5] | 3.1 [2.0,4.7] | 5.6 [4.1,7.8] | |
| A3 | 39.0 | 3.00 | 5 | 5.1 [3.7,7.1] | 8.8 [6.7,11.4] | 4.4 [3.1,6.2] | 8.1 [6.1,10.7] | |
| START B | B1 | 50.0 | 2.00 | 5 | 3.5 [2.5,4.8] | 5.5 [4.2,7.2] | 3.3 [2.4,4.6] | 5.2 [3.9,6.9] |
| B2 | 40.0 | 2.67 | 3 | 2.3 [1.5,3.4] | 4.3 [3.2,5.9] | 1.9 [1.2,3.0] | 3.8 [2.7,5.2] | |
START, UK standardization of breast radiotherapy.