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. 2018 Jun 21;91(1091):20180326. doi: 10.1259/bjr.20180326

Table 2.

Comparison of pre-clinical cell tracking methods, data adapted and modified from,5, 61,62 we noted that Ultrasound and CT are not well characterized for tracking cells

Modality Resolution Acquisition speed Sensitivity/cells detected Cell labeling agents
Optical 20 µm/poor at depth <Seconds μM/1000 Reporter gene/dyes (IcG, Cy, Luciferase)
Nuclear medicine 1000–2000 µm Minutes pM/10,000–100,000 Radionuclide (In111, Tc99m, 18F, 68Ga)
MRI 25–500 µm Minutes mM/10,000 Contrast agent (Gd, Mn, SPIO, 19F)
MPI 250–1400 µm Minutes 0.1 µM/10– 200 SPIO

MPI, magnetic particle imaging; SPIO, superparamagnetic iron oxide nanoparticle.