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. 2019 Apr 22;17:57. doi: 10.1186/s12951-019-0490-2

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Nucleic acid release profile studies. a Release profile data of antimiR-155 PS nucleic acid from PLGA NPs at indicated time points in a graph. All data were collected in triplicate (n = 3) and error reported as mean ± standard error (SE). b Electrophoretic mobility gel shift assay to quantify the release of antimiR-155 PS from PLGA nanoparticles at indicated time points. The samples were separated on 10% nondenaturing polyacrylamide gel and stained with SYBR-Gold