Table 5.
Effect of TSE on the biochemical parameters of animals.
| Normal | 100 mg | 250 mg | 500 mg | |
|---|---|---|---|---|
| Male | ||||
|
| ||||
| ALT (U/L) | 63.87±5.27 | 48.70±3.45 | 65.57±0.98 | 71.50±2.26 |
| AST (U/L) | 148.00±2.55 | 153.43±2.48 | 169.30±6.50 | 189.47±15.60∗∗ |
| AST/ALT | 0.67±0.52 | 1.47±0.28 | 0.83±0.44 | 1.67±0.29 |
| TBil (µmol/L) | 1.63±0.55 | 2.96±0.88 | 1.85±0.42 | 2.68±0.27 |
| DBil (µmol/L) | 0.95±0.05 | 1.49±0.65 | 0.98±0.03 | 1.04±0.17 |
| IBil (µmol/L) | 0.67±0.52 | 1.47±0.28 | 0.83±0.44 | 1.67±0.29 |
| Creat (µmol/L) | 28.50±6.22 | 24.27±1.19 | 49.67±9.19∗∗ | 23.03±4.95 |
| Urea (mmol/l) | 11.04±0.85 | 8.09±1.25 | 8.95±0.58 | 9.26±1.02 |
| K (mmol/L) | 7.30±0.45 | 6.27±0.19 | 7.00±0.35 | 6.83±0.44 |
| Na (mmol/L) | 143.00±0.43 | 142.43±0.55 | 142.90±0.42 | 143.80±1.95 |
| Cl (mmol/L) | 105.57±0.53 | 102.77±0.67 | 104.80±0.87 | 106.43±1.05 |
| TChol (mmol/L) | 1.87±0.07 | 2.13±0.26 | 2.11±0.21 | 2.04±0.09 |
| Trigs (mmol/L) | 1.19±0.15 | 1.35±0.29 | 1.14±0.12 | 1.33±0.16 |
| VLDL (mmol/L) | 0.53±0.09 | 0.60±0.15 | 0.50±0.06 | 0.60±0.10 |
| HDL (mmol/L) | 0.58±0.02 | 0.79±0.07 | 0.53±0.07 | 0.59±0.09 |
| LDL (mmol/L) | 0.74±0.03 | 0.73±0.31 | 1.06±0.16 | 0.85±0.11 |
| Glucose (mmol/L) | 1.72±0.32 | 2.48±0.21 | 3.02±0.33 | 4.60±0.77 |
| LDH (U/L) | 4617.76±101.23 | 4521.53±404.56 | 4340.33±184.88 | 4462.07±649.88 |
|
| ||||
| Female | ||||
|
| ||||
| ALT (U/L) | 56.70±4.22 | 49.97±2.98 | 56.63±3.86 | 46.20±2.46 |
| AST (U/L) | 149.77±8.24 | 143.07±5.01 | 144.37±19.11 | 169.17±10.95 |
| AST/ALT | 2.67±0.18 | 2.87±0.09 | 2.57±0.26 | 3.67±0.14 |
| TBil (µmol/L) | 1.36±0.27 | 1.91±0.43 | 1.68±0.21 | 3.31±0.46∗∗∗ |
| DBil (µmol/L) | 0.93±0.11 | 1.45±0.24 | 1.06±0.09 | 1.22±0.21 |
| IBil (µmol/L) | 0.43±0.18 | 0.80±0.40 | 0.63±0.02 | 2.07±0.42 |
| Creat (µmol/L) | 28.50±0.66 | 25.80±5.05 | 41.70±5.03∗∗ | 22.87±3.33 |
| Urea (mmol/l) | 10.61±0.46 | 12.61±0.82 | 11.64±1.20 | 7.55±1.45 |
| K (mmol/L) | 7.07±0.29 | 7.13±1.24 | 7.20±0.40 | 5.80±0.21 |
| Na (mmol/L) | 142.73±0.43 | 142.77±0.58 | 141.20±0.93 | 145.47±1.44 |
| Cl (mmol/L) | 106.33±0.80 | 106.97±1.30 | 105.97±0.81 | 109.13±1.33 |
| TChol (mmol/L) | 2.15±0.03 | 2.45±0.07 | 2.36±0.06 | 2.11±0.17 |
| Trigs (mmol/L) | 1.27±0.22 | 1.07±0.30 | 0.96±0.29 | 1.62±0.26 |
| VLDL (mmol/L) | 0.57±0.09 | 0.50±0.15 | 0.43±0.12 | 0.73±0.12 |
| HDL (mmol/L) | 0.87±0.11 | 0.71±0.27 | 0.76±0.08 | 0.43±0.04 |
| LDL (mmol/L) | 0.70±0.12 | 1.25±0.20 | 1.16±0.15 | 0.95±0.17 |
| Glucose (mmol/L) | 1.20±0.10 | 1.42±0.48 | 1.26±0.15 | 5.09±0.34 |
| LDH | 4052.10±101.65 | 3860.33±90.55 | 4039.20±239.98 | 3301.40±638.74 |
Mean±SEM (n=3); statistical significance; ∗p<0.5, ∗∗p<0.01, and ∗∗∗p<0.001 compared among the treated and normal groups.