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. 2019 Apr 8;2019:7253768. doi: 10.1155/2019/7253768

Table 1.

Moebius subjects' medical cases. The term “laterality” refers to the kind of facial paralysis that can be unilateral or bilateral; the sixth and seventh cranial nerves are usually involved, but other nerves may also be affected. “Associated pathologies” linked to Moebius syndrome can involve possible hand and foot anomalies, muscle hypotonia, hypoacusis, swallowing and speech problems, and Poland syndrome.

ID no. Sex Laterality Cranial nerves involved Additional functional deficits and associated pathologies
1 M Unilateral left VI, VII
2 M Bilateral VI, VII, III, IV Strabismus, hypotonia, hypoacusia of the right ear, speech deficit (articulation-phonetic disorders), right plagiocephaly, psychomotor delay, epileptic seizures, cardiac crisis
3 F Bilateral VI, VII, XII Foot malformations
4 F Unilateral left VI, VII, XII Speech deficit, club feet
5 M Bilateral VI, VII, XII Club foot, brain stem atrophy with enlargement of the fourth ventricle, hand deformities
6 F Unilateral right VI, VII, XII right Micrognathia, tongue hypoplasia
7 F Bilateral VI, VII Bilateral mixed hypoacusia, hypotonia, delayed growth, laryngomalacia, palatal schisis, coloboma of the right optic nerve
8 M Bilateral VI, VII, XII left Respiratory difficulties, micrognathia, hypotonia, psychomotor delay, club foot
9 M Bilateral VII No ocular deficits, speech delay