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. 2019 Apr 4;2019:8685312. doi: 10.1155/2019/8685312

Figure 1.

Figure 1

Interferon induction in normal and HIV-infected cells. (a) Interferon induces the induction of interferon-stimulated genes (ISG) through the activation of ISGF3. (b) HIV Vif leads to the degradation of STAT1 and Vpu, and Nef blocks phosphorylation of STAT1.