Table 2.
Phenotypic and genetic correlations between the glycated serum protein metrics and cardiometabolic traits measured in the Jirel pedigree.
| Trait pairs | Phenotypic correlation | Genetic correlation∗ | ||
|---|---|---|---|---|
| ρ p (SE) | p value | ρ g (SE) | p value | |
| GSP-SBP | 0.089 (0.024) | 2.08 × 10−4 | -0.027 (0.166) | 0.872 |
| GSP-DBP | 0.067 (0.024) | 0.0056 | -0.053 (0.161) | 0.742 |
| GSP-BMI | 0.047 (0.024) | 0.052 | 0.017 (0.122) | 0.891 |
| GSP-TC | 0.144 (0.024) | 1.78 × 10−9 | 0.351 (0.149) | 0.025 |
| GSP-HDLC | -0.019 (0.024) | 0.424 | -0.177 (0.161) | 0.273 |
| GSP-LDLC | 0.096 (0.024) | 8.05 × 10−5 | 0.263 (0.136) | 0.057 |
| %GA-SBP | 0.066 (0.024) | 0.0062 | -0.069 (0.177) | 0.689 |
| %GA-DBP | 0.020 (0.024) | 0.402 | -0.140 (0.172) | 0.407 |
| %GA-BMI | 0.006 (0.024) | 0.796 | -0.002 (0.128) | 0.988 |
| %GA-TC | 0.035 (0.024) | 0.148 | 0.289 (0.163) | 0.077 |
| %GA-HDLC | -0.106 (0.024) | 1.12 × 10−5 | -0.238 (0.166) | 0.162 |
| %GA-LDLC | -0.021 (0.024) | 0.382 | 0.072 (0.146) | 0.623 |
SE: standard error. ∗Additive genetic heritability estimates (h2: 0.149 to 0.536) for all cardiometabolic traits were significant (p values: 1.15 × 10−4 to 1.14 × 10−42).