Table 3.
The odds ratios for the presence of insulin resistance across AHI or Lp(a) quartiles.
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for linear trend | |
|---|---|---|---|---|---|
| AHI quartiles | |||||
| n (cases/participants) | 169/1,053 | 334/1,031 | 424/1,017 | 668/1,051 | — |
| Unadjusted | 1 | 2.51 (2.03, 3.10) | 3.74 (3.05, 4.61) | 9.12 (7.43, 11.25) | <0.001 |
| Adjusted | 1 | 1.61 (1.27, 2.05) | 1.92 (1.50, 2.46) | 2.87 (2.23, 3.70) | <0.001 |
| Lp(a) quartiles | |||||
| n (cases/participants) | 456/1,026 | 427/1,062 | 371/1,032 | 341/1,032 | — |
| Unadjusted | 1.62 (1.36, 1.94) | 1.35 (1.14, 1.63) | 1.14 (0.95, 1.36) | 1 | <0.001 |
| Adjusted | 1.40 (1.12, 1.74) | 1.21 (0.98, 1.50) | 1.16 (0.93, 1.43) | 1 | 0.029 |
Odds ratios, 95% confidence intervals, and P values were calculated using logistic regression analyses. Insulin resistance was defined as the HOMA-IR index > 3. AHI quartiles 1-4 correspond to the AHI range of ≤7, 7.1-28, 28.1-57, and >57 events/h, respectively. Lp(a) quartiles 1-4 correspond to the serum Lp(a) concentration range of ≤3.90, 3.91-7.40, 7.41-15.10, and >15.10 mg/dL, respectively. Adjusted variables include Lp(a) or AHI quartiles, age, gender, BMI, waist-to-hip circumference ratio, MAP, current smoking status, current drinking status, TC, TG, HDL-C, LDL-C, ApoA-I, and ApoB.