Table 3.
The C-indices for the nomogram and the five currently used staging systems for multiple myeloma to predict overall survival in patients.
| Staging systems | Training cohort | Validation cohort | ||
|---|---|---|---|---|
| C-index | 95% CI | C-index | 95% CI | |
| Nomogram | 0.749 | 0.693−0.805 | 0.711 | 0.650−0.772 |
| ISS | 0.576 | 0.515−0.637 | 0.637 | 0.553−0.720 |
| R-ISS | 0.625 | 0.567−0.683 | 0.651 | 0.566−0.736 |
| D-S | 0.567 | 0.510−0.624 | 0.529 | 0.446−0.612 |
| mSMART | 0.583 | 0.524−0.642 | 0.620 | 0.532−0.708 |
| IMWG | 0.513 | 0.453−0.573 | 0.578 | 0.484−0.672 |
Abbreviations: C-index, index of concordance; CI, confidence interval; ISS, International Staging System; R-ISS, Revised-International Staging System; D-S, Durie-Salmon Staging System; mSMART, Mayo Stratification of Myeloma and Risk-Adapted Therapy; IMWG, International Myeloma Working Group risk stratification.