Figure 1.

Schematic of obligately lytic, chronic, and latent strategies, give a population perspective (top) and individual perspective (bottom). Top, The nonlinear dynamics for each model are presented in Section 2. Bottom, The basic reproduction number accounts for complete cycles beginning with infected cells. In the obligately lytic case, only three virions of many infect cells, these are progeny, aka new mothers. In the chronic case, the mother cell divides once and two progeny virions infect new cells. In the latent case, the mother cell divides three times before it is removed. In all of these examples, the total reproduction number is the same, albeit with differing contributions from horizontal and vertical transmission routes.