Figure 4. Placement of the Reservoir Patch (A) and Active Patch (B) on a subject.
(A) Following active treatment (30 minutes), the passive drug-containing Reservoir Patch remained on the Subject for a twelve-hour treatment period. (B) Ultrasound patch (Active Patch) lying on top of the Reservoir Patch, following addition of reconstituted drug. The Active Patch was aligned with the reservoir using a rounded metal alignment band held during active treatment using medical adhesive bandage. The Control Sites for TEWL measurements are represented with a circle, and the general treatment areas (Patch Site) are represented with rectangles.