Table 4.
Results of the multiple regression analysis for all the variables in the model to predict triglyceride of fifth-grade WV children born full term using merged data from the Birth Score Project (1998–2003) and the CARDIAC Project (2010–2013)
| Full model |
Covariate model |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Unstandardized regression coefficients (95% Cl) | Standardized Beta | t Value | P-value | Adjusted R2 | Unstandardized regression coefficients (95% Cl) | Standardized beta | t Value | P-value | Adjusted R2 | |
| Intercept | 3.31 (2.97 to 3.64) | 0.00 | 19.3 | <0.0001 | 0.1499 | 3.17 (2.89–3.44) | 0 | 22.56 | <0.0001 | 0.1486 |
| Age (years) | 0.06 (0.04 to 0.09) | 0.06 | 4.4 | <0.0001 | 0.072 (0.05 to 0.10) | 0.06 | 6.08 | <0.0001 | ||
| Gender (male vs. female) | −0.11 (−0.14 to−0.08) | −0.10 | −8.24 | <0.0001 | −0.11 (−0.13 to−0.09) | −0.11 | −10.48 | <0.0001 | ||
| Race (White vs. others) | 0.14(0.09 to 0.19) | 0.07 | 5.3 | <0.0001 | 0.12(0.08 to 0.17) | 0.06 | 5.58 | <0.0001 | ||
| History of hypercholesterolemia | 0.07 (0.04 to 0.10) | 0.06 | 5.04 | <0.0001 | 0.07 (0.05 to 0.10) | 0.06 | 6.16 | <0.0001 | ||
| Number of previous pregnancies (≥ 1 vs. 0) | −0.04 (−0.07 to−0.02) | −0.04 | −3.12 | 0.0018 | −0.03 (−0.06 to−0.01) | −0.03 | −3.01 | 0.0026 | ||
| Maternal education (Years) | −0.010 (−0.017 to −0.004) | −0.04 | −3.16 | 0.0016 | −0.008 (−0.014 to −0.004) | −0.04 | −3.43 | 0.0006 | ||
| BMI percentile | 0.0065 (0.006–0.007) | 0.35 | 27.45 | <0.0001 | 0.0065 (0.006–0.007) | 0.35 | 33.72 | <0.0001 | ||
| Breastfed (yes vs. no) | −0.04 (−0.06 to−0.01) | −0.03 | −2.65 | 0.008 | ||||||
Only covariates that were significant in the Spearman’s correlation were used in the multiple regression analysis. Covariates included child’s age, gender, race, infant birth weight in grams, maternal education status at birth (1–17 years of education), maternal health insurance status at time of delivery (non-Medicaid vs. Medicaid), family history of hypercholesterolemia (yes vs. no), number of previous pregnancies assessed at birth (≥ 1 vs. 0), maternal smoking status during pregnancy (yes vs. no), weight gain during pregnancy in lbs. Covariates that were not significant in the Spearman’s correlation and were excluded: maternal age at birth of the index child, infant birth weight in grams, marital status of the mother at birth, number of prenatal care visits. Each non-significant covariate was deleted from the regression model one at a time. These included infant birth weight in grams, family history of hypercholesterolemia (yes vs. no), number of previous pregnancies assessed at birth (≥ 1 vs. 0), maternal smoking status during pregnancy (yes vs. no), weight gain during pregnancy in lbs
WV West Virginia, CI confidence interval, CVD cardiovascular disease, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDL low-density lipoprotein cholesterol, HDL high-density lipoprotein, non-HDL non-high-density lipoprotein cholesterol, TG triglycerides