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. 2019 Apr 13;25:2702–2717. doi: 10.12659/MSM.915018

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© Med Sci Monit, 2019

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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Photomicrographs of the histology of the patella and trochlea induced by patellar ligament shortening (PLS) surgery in the rat model of patellofemoral joint osteoarthritis (PFJOA). (A) Representative histological sections stained with Safranin O/fast green of the patellofemoral joint (PFJ) in the three rat study groups. Bilateral weight-bearing areas (a, lateral; c, medial) and non-weight-bearing areas b) of the patella and trochlea. (B) Analysis of the Osteoarthritis Research Society International (OARSI) score of the patella, trochlea, and both, respectively. The green arrow indicates reduced Safranin O staining. The red arrow indicates horizontal clefts and denudation. The black arrow indicates cartilage swelling. The yellow arrow indicates chondrocyte clones. The red arrowhead indicates irregularities in the cartilage surface. The short black arrow indicates a large erosion with fibrous tissue proliferation. Red bars=500 μm. Black bars=100 μm. Data are expressed as the median and interquartile range (IQR).