Table 1.

Frequency of ASCT2 expression in primary human colon cancers

	Number	(+) N =40	(−) N =57	Test statistic
Tissue type	115
				$\chi \frac{2}{1}=39.37,$
				P < 0.001
Normal		8 % (3)	72 % (41)
Primary		92 % (37)	28 % (16)

Normal vs primary samples. ASCT2 immunoreactivity was evaluated in tissues samples derived from 115 patients with primary colon cancer. Among tissues from patients with primary colon cancer, a total of 53 distinct colon cancers and 44 adjacent normal colon samples were evaluated. Across all normal colon tissue samples (n = 88), greater than 90 % of the samples were negative for ASCT2 immunoreactivity. In contrast, we found that approximately 70 % of primary colon cancers exhibited positive ASCT2 immunoreactivity