. Author manuscript; available in PMC: 2019 Apr 22.

Published in final edited form as: Mol Imaging Biol. 2017 Jun;19(3):421–428. doi: 10.1007/s11307-016-1008-z

Table 2.

Frequency of ASCT2 expression in human colon cancers liver metastases

	N	(+) N =24	(−) N =60	Test Statistic

Tissue Type	111
				$χ \frac{2}{1} = 21.42,$
				P < 0.001
Normal		12 % (3)	72 % (41)
Metastatic		88 % (21)	28 % (19)

Normal vs metastatic samples. ASCT2 immunoreactivity was evaluated in tissues samples derived from 111 patients with metastatic colon cancer. Among tissues from patients with metastatic colon cancer, a total of 40 metastases and 44 adjacent normal colon samples were evaluated Across all normal colon tissue samples (n = 88), greater than 90 % of the samples were negative for ASCT2 immunoreactivity. In contrast, we found that approximately 53 % of colon cancer metastases exhibited positive ASCT2 immunoreactivity