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. Author manuscript; available in PMC: 2019 Apr 22.
Published in final edited form as: Pediatr Dermatol. 2018 Mar 23;35(3):354–360. doi: 10.1111/pde.13454

TABLE 3.

Comparison of histopathologic features in childhood and adolescent melanomas

Histopathologic features Childhood melanomas Adolescent melanomas P-value
Breslow thickness, mm, median (range)  3.5 (0.9–85) 1.5 (0.5–36)  .20a
Mitotic index, figures/mm2, median (range)   5 (1–15)   2 (0–10)  .07a
Ulceration, n/N with reported features (%) 3/9 (33.3) 3/12 (25) >.99b
Lymphovascular invasion, n/N with reported features (%) 1/8 (12.5)  1/9 (11.1) >.99b
Neural invasion, n/N with reported features (%) 2/6 (33.3)  0/9 (0)  .14b

Results reported for all melanomas for which Breslow thickness, mitotic index, ulceration, lymphovascular invasion, and neural invasion were reported.

a

Mann-Whitney U-test.

b

Fisher exact test.