TABLE V.
Pt ID | Sample sitea | Sex | Age (years) | Smoking status | EGFR mutation | Biopsy status | TNM stage | Cell differentiation | |
---|---|---|---|---|---|---|---|---|---|
| |||||||||
E-Cadherin | Vimentin | ||||||||
1 | Lung primary | Female | 62 | No | Exon 21 | Positive | Positive | IB | Well or moderately |
Lung metastasis | Positive | Positive | |||||||
| |||||||||
2 | Lung primary | Female | 54 | No | Exon 19 | Positive | Negative | IV | Poorly |
Liver metastasis | Positive | Negative | |||||||
| |||||||||
3 | Lung primary | Male | 70 | Yes | Exon 19 | Positive | Negative | IV | Well or moderately |
Lung metastasis | Positive | Negative | |||||||
| |||||||||
4 | Lung primary | Male | 66 | Yes | Exon 19 | Positive | Negative | IV | Poorly |
Liver metastasis | Negative | Negative |
For all 4 patients, the first biopsy site was the primary lung lesion. The re-biopsy site depended on circumstances. For patients 1 and 3, the sample came from an intrapulmonary metastasis resulting from local progression; for patients 2 and 4, the sample came from liver because of distant metastasis.