Table 1. Table of parameters and values used in cellular Potts model (CPM) simulations.
See text for more detailed reasoning behind values.
| Parameter | Value | Reason |
|---|---|---|
| Total time T | 9 h | Experiments |
| Recording interval Δt | 15 min | Experiments |
| Background concentration c | 2.5 nM | Experiments |
| Concentration gradient g | 5 nM/mm | Experiments |
| Relaxed cell area A0 | 400 μm2 | Experiments |
| Lattice spacing ℓ | 2 μm | ∼100 sites per cell |
| Cell-environment contact energy α | 2 μm−1 | α ∼ ℓ−1 |
| Area deviation energy λ | 0.01 μm−1 | λ−1/2 ≪ A0 |
| Simulation time τ | 100 s | ℓ2/D ≪ τ < Δt |
| Total receptor number N | 10,000 | CI saturation |
| Bias strength ϵ | 56 | Calibrated via CI |
| Persistence strength η | 107 | Calibrated via DP |
| Polarization memory decay rate r | 0.01 s−1 | r ∼ τ−1 |