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(a) HER2+ and ER+ BT-474 cells were treated with both tamoxifen and trastuzumab while ER+ MCF-7 cells and HER2+ SK-BR-3 cells were only tretated with tamoxifen and trastuzumab respectively. There was only one common responsive miRNA among upregulated miRNAs; 11 miRNAs were commonly downregulated in all cell lines. The common responsive miRNAs are listed in b.
