Table 4. Prognostic factors for overall survival, n = 84 (log-rank test, multivariate Cox regression analysis).

KPS: Karnofsky performance status

*For example bone(s), example for more than one: liver and lung(s)

Parameter	Number	Percent	Median overall survival in months	Univariate p-value	Multivariate p-value
Female gender	40	47.6	6.0
Male gender	44	52.4	8.4	0.59	Not included
Symptomatic metastases	64	76.2	6.1
Imaging detected metastases	20	23.8	10.5	0.60	Not included
No extracranial metastases	30	35.7	11.0
One extracranial organ*	29	34.5	8.4
More than one extracranial organ	25	29.8	3.7	0.002	0.08
KPS 40-50	7	8.3	3.0
KPS 60	9	10.7	6.0
KPS 70	26	31.0	4.5
KPS 80	17	20.2	7.9
KPS 90-100	25	29.8	17.7	0.0001	0.0001
Age <=65 years	40	47.6	11.0
Age >=66 years	44	52.4	5.9	0.06	0.08
Single brain met.	25	29.8	11.4
Two brain met.	13	15.5	7.9
Three brain met.	16	19.1	5.6
4-9 brain met.	21	25.0	4.3
10 or more brain met.	9	10.7	3.0	0.02	0.05