Table 3.
Multivariable Models For Somewhat/Strongly Agree Response
| Endpoint | Variable | OR (95% CI) | p Value |
|---|---|---|---|
| Importance of drug-related genetic variants | Age group (overall) | 0.43 | |
| Age 56–65 v <=55 | 1.14 (0.77, 1.68) | 0.51 | |
| Age 66–75 v <=55 | 0.91 (0.61, 1.35) | 0.64 | |
| Age >75 v <=55 | 1.31 (0.81, 2.12) | 0.28 | |
| Men v Women | 1.48 (1.05, 2.09) | 0.024 | |
| Canada v USA | 1.21 (0.78, 1.86) | 0.39 | |
| Korea v USA | 0.10 (0.07, 0.14) | <0.001 | |
| Importance of other genetic variants | Age group (overall) | 0.51 | |
| Age 56–65 v <=55 | 1.29 (0.90, 1.85) | 0.17 | |
| Age 66–75 v <=55 | 1.03 (0.72, 1.50) | 0.86 | |
| Age >75 v <=55 | 1.16 (0.74, 1.80) | 0.51 | |
| Men v Women | 1.62 (1.18, 2.22) | 0.003 | |
| Canada v USA | 1.66 (1.13, 2.45) | 0.011 | |
| Korea v USA | 0.15 (0.11, 0.21) | <0.001 | |
| Comfort with genetic testing to guide decisions | Age group (overall) | 0.75 | |
| Age 56–65 v <=55 | 1.20 (0.82, 1.75) | 0.35 | |
| Age 66–75 v <=55 | 1.11 (0.75, 1.64) | 0.60 | |
| Age >75 v <=55 | 1.24 (0.78, 1.99) | 0.36 | |
| Men v Women | 1.42 (1.01, 1.98) | 0.041 | |
| Canada v USA | 1.37 (0.90, 2.09) | 0.14 | |
| Korea v USA | 0.11 (0.08, 0.15) | <0.001 | |
| Comfort sharing results with other physicians | Age group (overall) | 0.39 | |
| Age 56–65 v <=55 | 1.10 (0.75, 1.62) | 0.62 | |
| Age 66–75 v <=55 | 1.10 (0.74, 1.64) | 0.63 | |
| Age >75 v <=55 | 1.53 (0.94, 2.49) | 0.088 | |
| Men v Women | 1.31 (0.93, 1.85) | 0.12 | |
| Canada v USA | 1.43 (0.95, 2.14) | 0.087 | |
| Korea v USA | 0.06 (0.05, 0.09) | <0.001 | |
| Comfort with pharmacist having test results | Age group (overall) | 0.013 | |
| Age 56–65 v <=55 | 1.40 (1.00, 1.97) | 0.048 | |
| Age 66–75 v <=55 | 1.06 (0.75, 1.49) | 0.74 | |
| Age >75 v <=55 | 1.83 (1.20, 2.80) | 0.005 | |
| Men v Women | 1.53 (1.13, 2.06) | 0.006 | |
| Canada v USA | 3.31 (2.33, 4.70) | <0.001 | |
| Korea v USA | 0.18 (0.14, 0.24) | <0.001 | |
| Comfort with genetic tests in medical record | Age group (overall) | 0.11 | |
| Age 56–65 v <=55 | 1.36 (0.96, 1.92) | 0.085 | |
| Age 66–75 v <=55 | 1.23 (0.86, 1.76) | 0.26 | |
| Age >75 v <=55 | 1.69 (1.09, 2.62) | 0.020 | |
| Men v Women | 1.23 (0.90, 1.68) | 0.20 | |
| Canada v USA | 2.20 (1.52, 3.19) | <0.001 | |
| Korea v USA | 0.14 (0.11, 0.19) | <0.001 | |
| Comfort carrying test results on person | Age group (overall) | 0.078 | |
| Age 56–65 v <=55 | 1.16 (0.83, 1.63) | 0.38 | |
| Age 66–75 v <=55 | 1.12 (0.79, 1.58) | 0.53 | |
| Age >75 v <=55 | 1.76 (1.14, 2.70) | 0.010 | |
| Men v Women | 1.31 (0.97, 1.77) | 0.078 | |
| Canada v USA | 2.29 (1.64, 3.21) | <0.001 | |
| Korea v USA | 0.14 (0.10, 0.18) | <0.001 | |
| Confident in ability to understand genetics | Age group (overall) | 0.89 | |
| Age 56–65 v <=55 | 0.94 (0.65, 1.35) | 0.73 | |
| Age 66–75 v <=55 | 0.87 (0.60, 1.27) | 0.48 | |
| Age >75 v <=55 | 0.87 (0.55, 1.36) | 0.54 | |
| Men v Women | 1.21 (0.87, 1.66) | 0.25 | |
| Canada v USA | 1.88 (1.32, 2.68) | <0.001 | |
| Korea v USA | 0.08 (0.06, 0.11) | <0.001 |