Figure 2.
Dose-response effects of butylone and pentylone on [3H]neurotransmitter uptake in rat brain synaptosomes and cells transfected with human transporters. Data from rat brain synaptosomes are depicted in Panel A for [3H]DA uptake by DAT and Panel B for [3H]5-HT uptake by SERT. Data from HEK-293 cells are depicted in Panel C for [3H]DA uptake by human DAT and Panel D for [3H]5-HT uptake by human SERT. Effects of butylone and pentylone are shown as closed circles and open squares, respectively. Data are mean ± SD expressed as percent of control uptake, for n=3 experiments performed in triplicate.
