Figure 5.
Dose-response effects of butylone and pentylone to produce transporter-mediated currents at human DAT and SERT. The Y-axis represents normalized current obtained by dividing current obtained with drug treatment by the current obtained with a 10 μM concentration of the endogenous substrate. The X-axis represents drug concentration in log scale. Effects of butylone on DAT and SERT are represented by open and closed circles, whereas effects of pentylone on DAT and SERT are represented as open and closed squares. Data are mean ± SD for n=3 experiments.
