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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Psychopharmacology (Berl). 2018 Oct 22;236(3):953–962. doi: 10.1007/s00213-018-5075-5

Figure 6.

Figure 6.

Neurochemical and behavioral effects produced by butylone and pentylone in conscious rats undergoing microdialysis in the nucleus accumbens. Effects of drugs on extracellular dopamine (DA) are shown in Panel A while effects on extracellular 5-HT are shown in Panel B. Effects of drugs on forward locomotion (Motor) and repetitive movements (Stereotypy) are shown in Panels C and D. Arrows indicate time of intravenous injection: 1 mg/kg of butylone or pentylone was given at time zero followed by 3 mg/kg given 60 min later. Saline was injected at 1 mL/kg at the same time points. Data are mean ± SEM expressed a percent of basal preinjection values for N=6-7 rats/group. Filled symbols represent significant effects of drugs compared to saline treatment at specific time points, whereas asterisks represent significant differences compared to butylone at specific time points (p<0.05, Bonferroni’s test).