Table 4.
Individual NPI-Q domain by NPS and cognitive diagnosis sequence
| Domain | Never (%) | NPS before MCI (%) | NPS before dementia (%)∗ | NPS after dementia (%) |
|---|---|---|---|---|
| Depression | 982 (49) | 484 (24) | 318 (16) | 214 (11) |
| Night time | 1110 (56) | 381 (19) | 298 (15) | 209 (10) |
| Irritability | 1037 (52) | 415 (21) | 337 (17) | 209 (11) |
| Anxiety | 1164 (58) | 344 (17) | 312 (16) | 178 (9) |
| Appetite/eating behaviors | 1249 (63) | 274 (14) | 272 (14) | 203 (10) |
| Delusions | 1773 (89) | 41 (2) | 61 (3) | 123 (6) |
| Hallucinations | 1888 (95) | 15 (1) | 25 (1) | 70 (4) |
| Agitation | 1279 (64) | 256 (13) | 254 (13) | 209 (10) |
| Apathy | 1278 (64) | 241 (12) | 261 (13) | 218 (11) |
| Disinhibition | 1622 (81) | 114 (6) | 116 (6) | 146 (7) |
| Motor | 1769 (89) | 56 (3) | 61 (3) | 112 (6) |
| Elation | 1913 (96) | 31 (2) | 31 (2) | 23 (1) |
Abbreviations: MCI, Mild cognitive impairment; NPI-Q, Neuropsychiatric Inventory Questionnaire; NPS, neuropsychiatric symptom.
∗
Includes those who developed NPS after MCI (normal to MCI); NPS after MCI (normal to MCI to dementia); and NPS before dementia (normal to dementia).