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. 2018 Oct 17;22(3):518–525. doi: 10.1007/s10120-018-0887-x

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© The Author(s) 2018, corrected publication 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Representative images of homogeneously HER2 positive gastric cancer. a Hematoxylin-eosin stains shows differentiated adenocarcinoma. HER2 IHC shows that almost all tumor cells overexpress HER2 protein in each specimen corresponding to HE stains. Representative images of heterogeneously HER2 positive gastric cancer. b HER2 IHC shows that HER2 protein overexpressed in some specimens