Table 2.
Survival outcomes by multivariate analyisis
| Covariates | PFS | OS | ||
|---|---|---|---|---|
| HR 95% (CI) | p value | HR 95% (CI) | p value | |
| Age | 0.046 | 0.22 | ||
| 67 ≥ (44) | 1 (reference) | 1 (reference) | ||
| < 66 (43) | 1.69 (1.01–2.84) | 1.39 (0.82–2.35) | ||
| Platinum-based | 0.002 | 0.01 | ||
| Yes (80) | 1 (reference) | 1 (reference) | ||
| No (7) | 5.63 (2.26–13.99) | 3.15 (1.32–7.55) | ||
| HER2 heterogeneity | < 0.001 | < 0.001 | ||
| Yes (53) | 1 (reference) | 1 (reference) | ||
| No (34) | 0.43 (0.25–0.74) | 0.36 (0.20–0.63) | ||
HR Hazard ratio, 95% CI 95% confidential interval, PFS progression-free survival, OS overall survival