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. 2019 Mar 5;26(12):12247–12263. doi: 10.1007/s11356-019-04502-w

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 10 — Effect of SFN on the Ar-induced histological changes in the kidneys of control and experimental animals. a Control rats: normal control (NC) renal tissue histology is seen. b, c Ar-treated rats show degenerative changes including glomerular space (GS), tubular degeneration (TD), vacuolization (VC), hemorrhage (HM), glomerular atrophy, sinusoidal dilation (SD), and necrosis (NEC) in the medullary area of Ar-treated rats. d Ar-treated rats with SFN: effective prevention of degenerative changes and shrunken cytoplasm and nuclei of renal tissue. e Rats treated with SFN alone: renal tissue histology similar to control was observed. (H&E, ×40)