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. 2019 Mar 5;26(12):12247–12263. doi: 10.1007/s11356-019-04502-w

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 12 — Graphical abstract shows the protective mechanism of SFN against Ar-induced damage in the kidney tissue via PI3K/Akt-mediated Nrf2 signaling pathway