Fig. 7.

a Effect of SFN on Ar-induced changes in the expression of cell survival proteins Nrf2, Akt, and PI3K in control and experimental rats by western blot. Lane 1: Control. Lane 2: Ar (5 mg/kg/BW). Lane 3: SFN (80 mg/kg/BW) + Ar. Lane 4: SFN alone. b Effect of SFN on Nrf2, Akt, and PI3K protein band intensities scanned by densitometer. Values are expressed as mean ± SD for four groups of eight rats in each. Statistical significance was determined by one-way ANOVA (Duncan’s multiple range test). Values not sharing a common superscript letter (a–c) differ significantly at p < 0.05