Table 1.

Effects of the AHR and CAR antagonists on the control spontaneous caspase-3 activity and LDH release in 7 DIV neocortical cultures. Primary neocortical cultures were treated with the AHR antagonists α-naphtoflavone and CH223191 and the CAR antagonist CINPA (all 1 μM) for 6 h. The results were normalized to the absorbency in vehicle-treated cells and expressed as a percentage of the control. Each value represents the mean of three independent experiments ± SEM. The number of replicates in each experiment ranged from 6 to 8

Neocortical cultures 6 h exposure	α-Naphtoflavone (1 μM)	CH223191 (1 μM)	CINPA (1 μM)
Caspase-3 activity [%control]	110 ± 14	112 ± 10	112 ± 14
LDH release [%control]	92 ± 12	89 ± 13	90 ± 14