Table 2.

Results of Western blotting analysis of LCLs

Spot No.	Candidate marker	1st sample set (CON n = 30, SCZ n = 30)						2nd sample set (CON n = 30, SCZ n = 30)						Combinede (CON n = 60, SCZ n = 60)
		FCa	t-test P-valueb		Logistic regression analysis			FC	t-test P-value		Logistic regression analysis			FC	t-test P-value		Logistic regression analysis
					OR	P-value	AUC				OR	P-value	AUC				OR	P-value	AUC
1	KIF11	1.31	0.284	(S)	2.10	0.289	0.63
2	HSPA4L	0.62	0.017	(W)	0.50	0.029	0.64	0.73	0.015	(W)	0.05	0.021	0.65	0.65	<0.001	(W)	0.59	0.03	0.61
3	HSP90AB1	1.12	0.390	(S)	1.45	0.384	0.57
	PDXDC1	1.10	0.604	(S)	1.15	0.598	0.49
4	VPS35	0.88	0.295	(S)	0.39	0.296	0.55
5, 6, 7	MX1	1.39	0.006	(S)	9.26	0.011	0.72	1.32	0.006	(W)	12.76	0.012	0.68	1.35	<0.001	(W)	10.32	<0.001	0.70
8	LCP1	1.04	0.791	(S)	1.07	0.787	0.54
9	HARS	1.09	0.588	(S)	1.55	0.582	0.57
10	GLRX3	0.74	0.002	(W)	0.05	0.006	0.73	1.12	0.103	(S)	13.31	0.106	0.61	0.88	0.073	(S)	0.33	0.08	0.55
11	UROD	0.77	0.010	(S)	0.24	0.018	0.73	1.03	0.824	(W)	1.17	0.828	0.54	0.85	0.118	(S)	0.60	0.12	0.59
12	PPA1	0.99	0.953	(S)	0.97	0.952	0.50
13	ANXA5	0.88	0.105	(W)	0.32	0.109	0.61
14	MAPRE1	0.76	0.009	(S)	0.20	0.015	0.69	1.18	0.010	(S)	95.47	0.015	0.68	0.89	0.182	(S)	0.57	0.19	0.51
	EFHD2	0.99	0.908	(S)	0.95	0.906	0.47
	TBCB	0.68	0.024	(W)	0.20	0.034	0.66	0.95	0.628	(S)	0.68	0.622	0.57	0.82	0.035	(S)	0.36	0.04	0.60
15	UCHL1	0.97	0.919	(S)	0.99	0.917	0.54
16	APRT	0.59	0.248	(W)	0.90	0.356	0.49
17	IGHM	1.80	0.037	(W)	5.03	0.050	0.63	0.71	0.336	(W)	0.98	0.336	0.49	0.80	0.466	(S)	0.98	0.46	0.45
18	GART	0.75	0.022	(S)	0.15	0.031	0.66	0.73	0.002	(S)	0.02	0.005	0.74	0.74	<0.001	(W)	0.08	<0.001	0.70
19	EEF1G	1.16	0.154	(S)	2.35	0.158	0.65
20	LACTB2	1.10	0.358	(S)	1.76	0.356	0.56
	TATDN1	1.14	0.195	(W)	2.58	0.210	0.57

FC fold change, OR odds ratio (SCZ/CON), AUC the area under the receiver operating characteristic curves, Combined combined results of 1st sample set and 2nd sample set

^aFC = the ratio of the average intensity (SCZ/CON)

^bt-test P-value: the differentially expressed proteins were determined by Student’s t-test (S) or Welch’s t-test (W) (unpaired, two tailed)