Table 4.

Results of quantitative real-time PCR analysis of poly I:C-treated mice

Gene symbol	2 ha				24 hb
	PFC		HIP		PFC		HIP
	FCc	P-valued	FC	P-value	FC	P-value	FC	P-value
Candidate marker
Hspa4l	1.39	0.176	0.63	0.292	1.07	0.425	1.00	0.994
Mx1	2.53	0.039	1.80	0.043	1.03	0.804	0.85	0.243
Glrx3	1.07	0.266	0.99	0.763	1.19	0.109	1.13	0.126
Urod	0.97	0.754	0.90	0.171	1.13	0.091	1.13	0.259
Mapre1	1.02	0.913	0.95	0.458	1.05	0.758	0.82	0.022
Tbcb	0.97	0.879	0.86	0.390	1.01	0.964	0.96	0.676
Ighm	1.22	0.156	1.20	0.054	1.19	0.009	1.23	0.024
Gart	1.63	0.139	1.11	0.222	0.98	0.699	0.93	0.330
Proinflammatory mediator
Mx2	1.53	0.029	1.61	0.042	1.13	0.310	0.96	0.528
Ifna	1.35	0.347	1.26	0.265	0.87	0.439	0.67	0.069
Ifnb	1.44	0.280	1.21	0.392	0.87	0.391	0.64	0.039
Ifng	1.56	0.070	1.52	0.063	1.09	0.647	1.22	0.169
Il1b	1.34	0.171	1.52	0.014	0.98	0.854	1.30	0.076
Il6	1.03	0.931	1.24	0.432	0.62	0.013	0.62	0.089
Tnf	1.60	0.108	2.49	0.005	0.74	0.189	0.72	0.116
Nfkb1	0.94	0.377	0.90	0.278	1.00	0.990	0.99	0.972

PFC prefrontal cortex, HIP hippocampus, FC fold change

^a2 h: sacrificed 2 h after final treatment with saline (n = 6) or polyI:C (n = 6)

^b24 h: sacrificed 24 h after final treatment with saline (n = 6) or polyI:C (n = 6)

^cFC = the ratio of the average intensity (poly I:C/saline)

^dP-value: the differentially expressed proteins were determined by Student’s t-test