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. 2019 Apr 22;7:11. doi: 10.1038/s41413-019-0050-2

Fig. 2. Increased bone loss and altered structure of vertebral trabecular bones in Δ130–136 mice after ovariectomy.

Fig. 2

Three-dimensional micro-computed tomography (3D µCT) analysis of BV/TV (a), Tb.N (b), Tb.Th (c), and Tb.Sp (d) of fifth lumbar (L5) vertebral trabecular bone showed significantly increased bone loss in Δ130–136 mice compared to wild-type (WT) and R76W mice. Left panels show the corresponding percentage changes. Representative 3D µCT images of L5 vertebra of WT and transgenic groups were shown (e). Data shown are mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001. n = 6–7. BV/TV, bone volume fraction; Tb.N, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular spacing