FIGURE 6.

Effect of CBD on the release of glutamate (B,E), GABA (C,F) and D-Aspartate (A,D) in sham or mTBI mice at 14 and 60 days after trauma. The values of extracellular amino acids in the mPFC were expressed as pmol in 10 μl of perfusate. Each point represents the mean ± SEM of 3–4 animals per group. ^∗, ^# and ° indicate significant differences compared to sham/vehicle, sham/CBD 10 or TBI/vehicle, respectively. P < 0.05 was considered statistically significant. One- Way ANOVA, post hoc test Newman-Keuls Multiple Comparison.