Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The tumor microenvironment in NNKTL. NNKTL utilize CCL17/21, IL-9, IP-10, and soluble ICAM1 to proliferate/invade in an autocrine manner. These factors may be regulated by EBV LMP1. CD70 activation via soluble CD27 also mediate tumor proliferation. The downregulation of miR-15a mediates tumor progression by regulating surviving. Surrounding immune cells such as monocytes support NNKTL through IL-15 signaling.
