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. 2019 Apr 16;10:322. doi: 10.3389/fneur.2019.00322

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Copyright © 2019 Abbott, Merican, Pearce, Juric, Worsnop, Foster and Chambers.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The difference in rate extremes, between 0600-midday^* and 1800-midnight^*, was statistically significant: incidence rate ratio 7.26 (95% CI 2.52–28.64, P ≤ 0.001). (B) The difference in rate extremes, between 0800-midday^* and midnight-0400^*, was statistically significant: incidence rate ratio 5.52 (95% CI 1.78–22.67, P = 0.001).