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. 2019 Apr 16;10:338. doi: 10.3389/fgene.2019.00338

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Copyright © 2019 Masaki, Ikeda, Hata, Shiozawa, Kon, Ogawa, Suzuki, Hakuno, Takahashi and Kataoka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analyses of splicing changes in K562 cells stably expressing either wild-type or mutant SRSF2 protein. (A) Immunoblotting analyses of K562 cell lines stably expressing myc-tagged wild-type or mutant SRSF2 proteins. A myc-vector was used as a negative control. (B) Numbers of reads from RNA sequence analyses and mapping percentage of sequence tags. (C) Numbers of altered splicing events and genes identified by comparing with myc-vector transfected cells. (D) Venn diagram comparing the differentially spliced genes among myc-vector, WT and three SRSF2 mutants expressing cells.