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. 2019 Apr 16;13:360. doi: 10.3389/fnins.2019.00360

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Copyright © 2019 Márquez-Valadez, Aquino-Miranda, Quintero-Romero, Papacostas-Quintanilla, Bueno-Nava, López-Rubalcava, Díaz, Arias-Montaño and Molina-Hernández.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of chlorpheniramine administration to pregnant rats on the motor activity of 21-day-old offsprings. (A) Total crossings; (B) speed; and (C) distance traveled. Evaluated in the open field test under basal conditions and 30 min after the administration of meta-amphetamine (1 mg/kg, i.p.) in male and female P21 offsprings from control and chlorpheniramine-treated (Chlo) rats. Values are means ± SEM from the indicated number of animals. P-values were obtained after two-tailed unpaired Student’s t-test; n.s., non-significant.