Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course

. 2019 Apr 16;10:368. doi: 10.3389/fneur.2019.00368

Imaging findings	NIHSS deterioration or no change* (n = 78)	NIHSS improvement or NIHSS = 0* (n = 110)
IS in ACA or MCA territory	50 (64.1%)	63 (57.3%)	0.346^a
IS in vertebrobasilar territory	21 (26.9%)	34 (30.9%)	0.554^a
No IS in FU-BI	11 (14.1%)	24 (21.8%)	0.181^a
HI 1	6 (7.7%)	6 (5.5%)	0.536^a
HI 2	8 (10.3%)	1 (0.9%)	0.003^a
PH 1	1 (1.3%)	2 (1.8%)	0.773^a
PH 2	6 (7.7%)	2 (1.8%)	0.049^a
Volume of PH in ml, median [IQR]	29.5 [5.6–95.4]	1.5 [0.6–13.4]	0.059^c

Results are presented as p-values using χ² Pearson ^(a), Kruskal-Wallis ^(b) or Mann–Whitney U test ^(c) when appropriate. ^*24 h after systemic rt-PA application; ACA, anterior cerebral artery; FU-BI, routine follow-up brain imaging after 12–36 h; HI, Hemorrhagic infarction; IS, ischemic stroke; MCA, medial cerebral artery; NIHSS, National Institutes of Health Stroke Scale; PH, Parenchymal hematoma.