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. 2019 Apr 16;10:436. doi: 10.3389/fphys.2019.00436

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Copyright © 2019 Parry, Mobley, Mumford, Romero, Haun, Zhang, Roberson, Zempleni, Ferrando, Vechetti, McCarthy, Young, Roberts and Kavazis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Rotarod performance between treatments over time. These data show rotarod performance prior to (PRE) and following (POST) the 28-day feeding intervention in ERS (A) and ERD (B). (C) Shows PRE to POST delta scores. Notably, only a significant main effect of time was observed. Group mean ± parenthesized standard deviation values are presented above all data points. ERS, EVs and RNA-sufficient; ERD, EVs and RNA-depleted.