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. 2019 Apr 16;10:436. doi: 10.3389/fphys.2019.00436

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Copyright © 2019 Parry, Mobley, Mumford, Romero, Haun, Zhang, Roberson, Zempleni, Ferrando, Vechetti, McCarthy, Young, Roberts and Kavazis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome and miRNA differences between treatments. Data in the figure demonstrate transcriptome-wide and miRNA differences between treatments. Only 22 mRNAs were greater in ERS versus ERD rats (thresholds for significance listed in Section “Materials and Methods”) (A), whereas 55 mRNAs were greater in ERD versus ERS rats (B). (C) Demonstrates that six rat miRNAs were different between treatments, whereas two bovine miRNAs were different. ERS, EVs and RNA-sufficient; ERD, EVs and RNA-depleted; NE, not expressed at a detectable level.