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. 2019 Apr 16;10:228. doi: 10.3389/fendo.2019.00228

Figure 5.

Figure 5

The effect of AG on bone formation in vivo. OVX mice were treated with different doses of AG for 4 weeks. (A) Representative images of bone formation at the distal femur examined using double staining with xylenol orange and calcein green in AG-treated mice and OVX mice. (B) The values of MAR, BFR/BS, Ob.S/BS, and Ob.N/B.Pm at the isolated distal femur from AG-treated mice and OVX mice determined using bone histomorphometry analysis. (C) Representative images of the distal femur metaphysis in AG-treated mice and OVX mice reconstructed using micro-CT. Scar bars, 0.2 mm. (D) The values of BMD, BV/TV, Tb.Th., and Tb.N. at the distal femur metaphysis in AG-treated mice and OVX mice using micro-CT. *P < 0.05, **P < 0.01 compared with the corresponding control group. N = 8 for each group.